Lots of fine deer cartridges in the .25 to .28 range - the best shoot flat (ballistic efficiency) and are tidy (powder efficiency). Seem to keep finding that the .25:06 is at its overall best with bullet near 120 grs. Lighter = faster, but normally not better performance on game.
The fellows who like the old .243 usually will horn in on these threads to try to convince about their favorite, but it is getting past its peak at 100 grains, even with the better bullets. Something in physics tells the story about 120 grains vs, 100 at generally same velocity. Story continues upward.
For deer and similar, 25:06 has been my first choice for 30 years.
