13 grs of HS-6 and the RCBS 270 SAA (goes 283 grs as purchased) goes a bit over 1000 fps in my 4" 25-5. A a fairly mild load that will do all I will ever need from the combo. That bullet has become my go to in my 45 Colt's.
+1. This load should handle almost any hunting chore. If you need more, there's always the .475's and .500's.
