My 300 wsm's have all loved H4350 powder with 165's and 180's. Here is a group I shot with one of my 300 wsm's that I sold to gunnut308 a while back:
Here's the same load that I double checked prior to my 2011 mule deer hunt. This is another 10 shot group, but was shot in a little wind. I took my buck at 600 lrf yards that year:
Same load at 160 yards:
My new 300 WSM isn't as accurate as the older FN pbr, but it's a lot lighter. Here is a 180gr. Nosler partition load I use with the H4350 powder:
However, lately I've been using a lot of IMR 4350 in my rifles (270 win, 30-06, 300 WSM, 338 win.. etc. etc...) since it's been easier to find: