On .45 ACP shot shells. The old Remington crimped #12 load was durable, no cracked plactic cases. As stated, they don't cycle so one round is the limit. Just pull the magazine before firing and get another one from the ammo wallet or dump pouch to finish the job, or just reload the chamber. One chambered round in .45 auto or one round in first cylinder of S&W 25 or 625 gives peace of mind. I rather think you'd guarantee addling the snake and then finish with ball if it came to that. Not ricocheting a ball round into livestock or equipment is the true plus.