I had a very nice Jovino, round butt, 3" S&W Model 624 that Elmer influenced me to rattle loose with way too much 2400 and hard cast 429421's.
I never did blow up a revolver with Elmer's loads. but I punched enough of 'em through model 24's and Model 29's to find out that you can definitely loosen up an N frame .44.
People can argue with me all they want, but a steady diet of 22 grains of 2400 capped by a Lyman 429421 will make a Model 29 rattle like a coffee can full of marbles in pretty damn short order.
I finally started using big frame Rugers for Elmer's loads.
I cooked the forcing cone out a few Superblackhawks with his loads, but I never shot one loose.
Well,...the grip frame would shoot loose, but not after I started using Locktite on the screws.
