I've hunted primarily with a standard .280 Mountain Rifle for twenty years and it's always done everything I've asked of it. I wouldn't re-chamber a 22-24" barrel for a 280AI but I would build one from scratch using a reasonable weight 26". I don't hump the mountains like I once did so a little longer/heavier barrel is not a bad thing. For me it's going to be a tossup between the 280AI and a 7LRM (or something close to it). Have an extra action available in each size. Not sure if I want to beat myself up burning the additional powder in a mag case.