I don't see any difference. 40 grain Ballistic Tips kill deer the same out of my 14 twist as they do out of my 8. They also kill deer about the same as a 338. And pretty much everything in between. A bullet through the heart/lungs results in a short death run with a piled up deer at the end.
A good friend was in on 20 some elk kills this year (many of them big bulls), with everything from his 243 shooting 85 TSXs to various Ultra Uber Awesome Mags. He noted the 243 worked about the same as the fire breathers.
This killing stuff isn't hard, put a decent bullet in the right place and stuff dies promptly. Put a bullet somewhere else and it doesn't.
