Aaaaahhhh yes, the Big Medicine!
That round made quite a reputation with a 300 grain bullet and fairly brisk velocities.
I knqw the .45-70 does pretty good with a 300 grainer and 2K+ velocity, but with a better sectional density, the .405 should dig deeper. You have to go to a bullet weight of 380 grains with the .45-70 to equal the .405's 300 grain SD.
Vic,,I have a custom 400 gr gas check mold on order for the 405 just to play around with..Like Gunner I'm a Hindenburg fan in all big bores..the bigger the better ! Only question will it stabilize? Wife said what can I get you for Christmas you don't already have two times over so the mold is inbound .