The .458's have a lot of bullets available for them. Why not load try a 300gn TSX for the smaller stuff, and then a 500-550gn for big critters. You could sight in for the 300gn bullets, and the 500's might only be an inch or 2 low at 50 yards where DG is shot. Might be easier to carry 1 rifle and 2 different loads than 2 rifles.
