John - I'm going to be brave and see if my old shoulder still tolerates the 375 Number One, 'cause it's such a cool rifle.
If not.. the 30-06 will get the nod. That danged Remington is a great rifle for a hunter. Accurate. Powerful enough. Easy to use. Reliable... And very successful in the game fields.
The 375 is major league cool though. And in the past I've shot it pretty danged well. I seem to be aging faster than the rifle. We will see.