The PHs I used 10-20 years ago were cheap and accurate, but I'd never use them on anything bigger than deer--and even then only if the deer was broadside. Unless Sierra's done something since then to make them hold together better and penetrate deeper, I'll continue to use something tougher like Accubonds.
I would use Sierra seconds before I would use Accubond firsts... I have never seen an Accubond exit hole.
