Shot many with various 243s and 6BR. BR took a deer at 400 yds, ranged. Used a 105 Amax....

That said, my fave all around, near and far is the 95 Nosler BT...also in the WW Factory Silvertip load.
Many bullets work, I have even used a 70 TNT successfully in both of the above...as well as others like the 85 BTHP SIerra, 100 NPT and 100 Sierra BTSP.

The 80 TTSX and 85 XBT are Wicked, and Deadly but lower in BC, so would limit to around 300 yds myself. Good hunting!

Simply KNOW what your limits are of the bullet you are using...Soft Bullets go into Soft targets, harder ones like Barnes Mono and Nosler Partition can drive thru bone much better when needed. SHOT PLACEMENT is Key as with any other round/bullet.