Well the 06 has killed a few animals as well as humans. 280AI is similar to 7mm Rem Mag, long considered the best long range belted magnum cartridge in the field. Coincidentally it was developed to obtain the same energy down range as an 06 with better long range capability. Neither will let you down if you do your part. FWIW the 06 is probably a better cartridge if you are comparing a 22 inch barreled action.
Last edited by Rossimp; 11/23/19.
