I’m not sure whether it’s typical of the breed, but at one point JM Marlins in 45LC had quite large chambers and barrel dimensions. They were also equipped with a fairly fast twist barrel (1 in 16” IIRC).
The upshot was accuracy with normal 45LC cast loads was poor. One rifle I had experience with responded well to using 350 gr cast pills designed for the 45/70 (they were 0.458 diameter). The loads using the cast 45/70 pills were a big improvement in accuracy.
