Ammo availability is something I'll need to consider. My understanding is that .300 BLK is compatible with standard 5.56 AR mags, of which I already have a decent supply. 7.62x39 requires different mags, correct?

I don't know anything about suppressors. I would be looking for the "F150 equivalent" of suppressors - neither the cheapest nor most expensive, durable with a proven track record and good bang-for-the-buck value.