I’ve killed them with everything I hunt deer/elk with (340wby, 300wby, 300wm, 06 and a MZ. If you’re worried about meat loss, stay away from the shoulder. Personally, in 308, I thing 165g Interlocs would meet your criteria perfectly. For what it’s worth, if youR focus is on the meat, get it gutted/skinned and on ice as quick as you can. In my experience, antelope is outstanding if you can cool it down quick enough. We literally hunted with big coolers/ice in the back of the truck. If you don’t, you’ll be missing out on tender delicate meat. It seems to go south a lot quicker than deer.