I have only killed 4 antelope. Hardly an expert, but they are not hard to kill with a well placed bullet. The three rifles I used were .257 Weatherby, .270 Winchester, and 7x57 Mauser, twice. All worked fine.
Today there are so many good cartridges to pick from it would be hard to go wrong with any of them. My sentimental choice is my #1, 7x57 with 150 gr BT.
My favorite game animal, fun to hunt and the weather can be pretty nice.