Mark V synthetic. My preferred load was the factory 210 partitions at 3250. It would regularly clover leaf and accounted for my longest shots on deer and antelope. Sadly, Weatherby no longer makes these loads and I’ve been unable to match accuracy and velocity at the the same time. I’m presently playing with 225 accubonds and partitions using RL26. I’m making progress but not done tweaking COAL. They’ll shoot well enough....but not what I’ve come to expect from the rifle.