My experience is 1" 5 shot groups at 50 yards for the average 22 rifle will translate to 5" groups at 100 yards.
The bullet goes subsonic and gets disturbed ~~75 yards.
The guys serious about 100 yards with 22LR, will shoot sub sonic ammo and lob those slow bullets in with lots of trajectory.
This creates a great long range opportunity for 17M2, 17HMR, and 22WMR....... but so far 22LR is still selling.