With virtually 100% weight retention I’ve moved from the 168gr. TTSX down to the 150gr. TTSX in my 30-06. It’s my anything from mice to moose bullet. I get 3000fps out of my 24” barrel with Big Game powder and 5 shot groups well under an inch! I’d have no issue using them in any 300Mag!
Elk Country
I'd run a 150 in a 308w. No need for a 168 or 180. Speed is what works well with these mono metals..