Ballistics typed on paper is not what always happens in hunting conditions.

What do you think would put an elk down quicker at 100 yards...........
A 220 Swift with with a 55 grain bullet or a 410 grain from a 45-70?

220 Swift energy is 1,004 by the book.
45-70 energy is 895.

I have yet to see a grizzly guide use a 220 Swift, but many carry a 45-70. Yeah I know newer guns can handle potent 45-70 loads, but I have used factory Remington ammo (to old load pressures) in my original 1873 trapdoor to take several elk.