The first 25 years of my deer hunting was done with a Rem 760 30-06 with a 2x7 Weaver in swing-off mounts, well that is not exactly true the first 3 years are so was iron sights, all with 180gr round nose or 220 round nose (just because).
I hunted a lot of years with on 06 and pretty much used 180 gr RNs, IF I could not find any 220 grain RN on the shelves.
Took deer out to 300 yds with those 220 gr RNs. They just work, period.
Also carried a 2 x 7 scope on top of my bolt action rifle ( a Browning A Bolt ), but mine was a Leupold Shot Gun Scope.
In this stuff, I liked those thicker set of crosshairs.
As I've aged, I've migrated down to 6mm and 6.5 mm. Last two deer I've taken, was one with a 6.5 Grendel, handloaded with a 140 gr Speer and the one this past season, was with a 6 x 45 and a 95 grain ballistic tip. Both of those were bang flops.
