Certainly is a lot of "passion" here over the .458! That's a good thing! It helps keep our sport alive.

I have a CZ in .458 Win., and as CZ550 noted, the throat is unusually long in those rifles, allowing the handloader to seat bullets farther out. That pretty much eliminates the compression issue. Mine loves 72 grns. of H4895 under the 450 grn. TSX. This load gives me a consistent 2225 fps., and 1 1/2" groups at 100 yds., and shoots to the same point of impact whether it's 100 degrees or 15 below. While I have never killed an animal with this rifle, my common sense leads me to believe this load would be up for any challenge that presented itself, and I would be confident in it.

Keep the passion guys! I've enjoyed the read!