You will probably be 1" low at 25. The error of angle increases with distance. There are 2 places where the trajectory will cross the line of sight; both depending on the ballistic coefficient, velocity and sight height over bore. Remember, 1 minute at 100 yards is an inch, at 200 it is 2 inches. I feel that actually the other variables mean that 1 inch at 100 won't translate to 3 inches at 300; the group will be something of a increasing curved cone (someone find the name for this, please).