As most of us have too many rifles to remember what rifle does what at what distance, it would be wise to do your preferred sight in at 100 yards, then shoot at 25 yards, note the rifle's exact point of impact and record it for future reference. This way, you can perform a 25 yard zero if necessary.
My local outdoor range is fifty yards. I've found that most of my rifles, when sighted in two inches high at 100 yards, are an inch high at 50 yards. This works for me as most shooting in the eastern woods is within 100 yards.
This makes sense to me. The closer you are to your muzzle, the larger the error at increased distances.
