MontanaMarine,
That's generally how I use QL as well anymore, on the rare occasions I use it. I much prefer to use pressure-tested data, though!
In regards to the original question, the .270 will be capable of a little more muzzle velocity, which pretty much compensates for the difference in in BC out to 550.
Hence the reason I sold a bunch of wildcats and loaded 500+ rounds of the Hornady 140 BTSP over 58 grains of H4831 SC for my 270 and just called it good.
I wish I could shoot well enough that the difference at 500 yards would make a difference.....