There are 12 gauge slugs available that will outperform anything you can load in a .30-06 but Brenneke's aren't the ones. The Dixie Terminator 2 3/4" slug load fires a 730 gr. hardcast slug at 1250 fps out of a 20" rifled slug barrel. The Dixie IXL-DGS {dangerous game slug} 3" slug load uses an 870 gr. hard cast slug at 1200 fps from a 20" slug barrel. I've seen tests of these loads {DGS} where they were fired into various test media studded with heavy cattle bones and they penetrated deeper and left a larger diameter wound channel than a 400 gr. bullet out of a 416 Rem. Mag.. Those are the slugs I would load for defense in big bear country. Just Google "Dixie slugs" and take a look.