IMHO, which is only based on seeing a few elk killed with it and putting about 600-700 of the damn things downrange out to 625 yards, the 225-gn Accubond is one of those bullets that stands out as arguably "best"... there's a lot of good things coming together in that bullet.
The elk killed by it in our camp went down DRT, at ranges in the 250-300 yd range. I don't have any personal experience with what it does at very close range- though Calvin's RUM experience at ~200 yds on a brown bear gets close to simulating a 338WM at close range...
Very well said Jeff. One thing about the 338 is it works wonderfully on elk with just about any bullet. I like the heavy 250 gr. sierra gameking because I know it produces DRT's and others like the lighter bullets because they think they "kill faster" for some reason
. The 225 is right in the middle and should be golden in the 338. I'd use it with no qualms whatsoever.