John, I've got 3 308's and 1 30-06 that's going to get rebarreled. I doubt I'll ever own another 30-06.
In the 308, I'm a 165 gr bullet guy, but I don't use mono's.
Also, it's not hard to get 2,650 with a 180 and several powders from a 22" barrel, though I have yet to see the need for more than a 165 in the 308. My last two bulls, a 6x6 and 7x7, both fell to 165's from my Kimber MT 308.