I have 3 in use on deer just now. 243, 6.5x57R and 270. They have been 100% success on the Tasmanian Fallow deer. No doubt overgunning but that's the rules here.
Factory Norma Oryx 100gr in 243, other 2 are hand loads. 120gr Pro Hunter over H4895 35grs approx 2600fps and 150gr Sierra SPSBT over IMR 4831 52.5grs approx 2700fps in 270.