I have a 7-08, don't have a 280.
But the 280 is a fine round, the .280 AI gets pretty close to the 7RM in a more efficient package.
I guess it boils down to the individual gun, SA vs. LA.
My 7-08 is a Bobby Hart built 700 in a Hunters Edge. It's a mighty nice rifle and right now, my go to WT and hog gun.
But, as a Loony, that's always subject to change...
DF