Really, I would recommend a .243 loaded with 85 TSX, 95, or 100 NP. These bullets put the .243 on steroids.
Jack
A .243 with 8 twist and a 3" box would be the way I'd want it. Otherwise, I'd probably go with something else.
And I'd see what it would do with new powders and 100+ gr. bullets.
DF
