Let's see now..... The original question was; "25-06 load for mule deer and whitetails"..... That's not too complicated for my simple mind. Try the 117 grain Sierra Pro-Hunter #1640 IIRC, with a healthy dose of RL-22. My Ruger 77 loves it... So then I love it too. Not that a good hundred grainer wouldn't work on Mulies & Whitetails. It's just that my Ruger prefers stuff in the 115-120 gr. range. YMMV.