My Uncle John was a cowboy and rancher, who guided many hunters, over a lot of country, for many years.
All he ever carried was a Savage 99 300 Savage. Although it had only the original iron sights, he had exceptional eyesight, and never needed a scope.
I once saw him drop a bull elk, up near Raton, with a single shot to the neck - at 325 yards. Then the work began!
He also used it guiding antelope hunters - and am sure he cleaned up many "messes" over the years.