Sure thing,I use Hornady cases,Federal LR magnum primers,140 grain Berger VLD hunting bullets and 62.4 grains of Ramshot Magnum powder.Maxload right out of Ramshots reloading Manual.This is from a 22" Tikka barrel.I have it sighted 2 1/2" high at 100 yards and hold on center of body out to about 325 yards.Puts the smack down on Mule Deer.( NOT JB)