I think it depends a lot on the bullet you choose. ie, your charged by a huge grizzly. You wand the 300 win with a 200gr bullet or the 338 win with a 250gr bullet? That's not to say the 200gr bullet probably won't work, I'm sure it will but I also think a 338 dia 250 gr bullet will work better. On an elk at even 200yds, results will be the same if you do your part.
