Hello Jorge!
Indeed!
Used my 1895 405 to launch a 300grain NF cup point solid on a large water buff and it hit the ground dead! All senses went into slo mo and I can still see the critters head bounce as it hit the ground. Bullet took out both shoulders and messed up all insides nearby.
I was going to use that load on my Cape Buff hunt but a couple of buddies talked me into the 400 grain game. One of them yelled "stop here" when I reached 2076 fps while load testing - it seemed that was his regulation load for his 450/400 DR that had taken multiple ele and buff in Africa. It worked for me too.