10-22 for the kids is sighted at 75 yds with a Bushnell Trophy 4-12x40.
Dad's old 572 is sighted at 100 yds with an old 3-9x32 Simmons, and it will do for heart shots on a feral tom cat at that range. Or at least it would six years ago when I last grabbed it for the task.
Just out of High School, I bought a Winchester 190. I kept it zeroed at 100 yds, and put several bricks of ammo through Campbell's Soup cans at that range the summer of '76.
For 50 years, I have found it as easy to hold under at midrange as it is to hold over at extended range.