I'll use a heaver constructed bullet everytime. I have used alot of 22 cals on deer and they leave a great big wound channel, but I feel safer with a 165 308 bullet everytime on deer, or better yet a 250 round nose out of a 358. I like a entry and a exit. That means I have 2 blood trails. I have never lost one with one going in and one out. I've had to look hard for a couple with only an entry.

Ed