All your concerns of shotgunners shooting through leaves and thicker cover in hopes of killing a squirrel and only wounding it instead has nothing to do with the weapon and everything to do with the hunter. That same hunter that doesn't take clear shots with a shotgun won't take clear shots with a .22 either. That hunter will shoot beyond his capabilities with whatever the weapon and will wound game regardless.
Every normal man must be tempted, at times, to spit on his hands, hoist the black flag, and begin slitting throats.
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