Always thought the .40 was a solution to a non-existent problem. In 9mm sized guns, it has more recoil than a .45 and those guns will wear out WAY faster than a 9mm. .40 S&W is a notorious gun killer. That said, it's a very capable cartridge should you be inclined, and it will get the job done just fine. I just don't think the trade off's are really attractive for that cartridge (and others). Handguns are rather unimpressive when it comes to "stopping"...they all kill just fine, but they don't stop well. So I think most have determined that more bullets is more beneficial than bigger bullets. Of course this is an argument that goes back a century or more, and they'll be debating this crap long after I'm gone. I have always favored hi-cap 9mm's...but that doesn't mean the other cartridges won't get it done just fine..