Interesting
I started using this combination 20 years ago when cimetidine first came out
While diphenhydramine is listed as an antihistamine, its primary pharmacology is in the lymphatic system working on T cells. So Im not surprised people are trying it for this.
The pharmacotherapeutics of a lot of drugs haven't been studied -no money in it. An example of one, which Im sure readers are familiar with is acetaminophen. Many speculations as to its analgesic action.
