The largest users of diphenhydramine are mommies who use it to make their kids sleepy at bedtime. Blocks acetylcholine. No CNS effects. No barbiturate habituation.
Getting back to cannabinoids --- When they have been around as long as some of the mentioned drugs, have the safety record, and get a price range that's reasonable------ there will be a new drug out to take there place.
Currently they are a classic example of the placebo effect, with the addition of being something new and out of the ordinary
