I generally try to tuck it in low and behind the shoulder on a broadside presentation. I don't care if they run a little. They end up well bled out and I don't spoil a lot of meat that way. This past year I did take a high shoulder shot on one buck. For a couple of reasons I wanted him DRT. .308, 165 grain BT, yanked the rug right out from under him but cost me shoulder steaks on both sides.
