Well, I haven't tried it yet myself, other than finding out 53gr TSX's will shoot okay in my .22-250. I was too busy with other projects this past year.
In fairness to the naysayers, lots of experienced writers have previously recommended against them. I think as late as the Nosler 4th manual, John Nosler, Sr. wrote of using a .22 centerfire on deer, didn't like the results, and spoke against the practice. I think it was after he retired that Nosler finally brought out a .22 cal Partition. Some years later Finn Aagard wrote of using TBBC's on deer, and things snowballed after that with the new Partition and the TSX. Enough people have reported good results that clearly, .22 centerfires do work well on deer.
