I can vouch for the fact that .30-06 150's will come apart on the shoulder of a Bull moose (friends rifle, I was trying to kill a Moose with a 30-30 but it was out of range. Ended up killing it in a charge with the 30-30) but the 220 will punch clean through a Cow Moose. I still had to wait for the Moose to die when I got up to it. I shot a very large Bull with the 350 grain Interlock out of a .450 Marlin and he was dead by the time I could get to him. That's the only time I ever seen a Moose die that quick.
