Back in the Eighties we used to have a lot of trouble with the 180 Core-Lokt round nose out of the .30-06 not expanding well on deer. I shot a buck behind the shoulder and it went 200 yards. When I found it I still had to finish it. We had several examples of this and then my dad shot a 130 class buck and it made it a couple hundred yards onto a neighboring property. He couldn't get permission to go on and get his buck. After that we switched to 150 Core-Lokts and all the problems went away.
