Either will work both in Africa and America. I've shot plains game with both and never had a problem.

Impala shot with a Ruger #1 in 7x57
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Western Roan for with a Rem Model 700 Classic in 375 H&H
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Personally, I have a soft spot for the 375 because if you ever decide to hunt dangerous game it is normally the minimum legal caliber you can take. Like the old saying goes, beware the man that only shoots one gun.

I use a 375 H&H for just about everything anymore for that very reason. I know where it hits and I know what it can do. Remember a gun that will kill an elephant will also kill a deer but the reverse isn't always true. And before anyone goes off about WDM Bell and all the elephants he shot with a 7x57 it has to be pointed out that was a different era and doing such a thing isn't legal anymore.

Last edited by Pirate; 09/24/14.
Be careful what you ask for because you just may get it someday.