When I was in High School, buddy was driving his pickup through a plowed field chasing jackrabbits at about 20 mph. Three buddies in the back all with semi-auto rifles couldn't hit the last rabbit we were chasing and all ran their guns empty.
Buddy driving says to me "shoot that SOB!" So I'm riding shotgun on the passenger side, and I stick my Colt Scout .22 SA Revolver out the window one handed and with the first shot drop the rabbit dead at 30 yards with the truck bouncing across the freshly plowed field at 20 mph