I've killed coyotes with nearly every rifle I've ever owned, they all work, some just better than others.

Right now I have a 22-250AI, 223AI and a 204 Ruger all in Kimber Montana's, about the most perfect calling rifle ever made. Out of those the 223AI is becoming my favorite but the other 2 will reach further and the 204 is easier on fur. I also have a few AR's in standard 223/5.56 and they work too.

Some that I regret selling sometimes are a 243AI in a Remington 700 Mountain Guide and a Sako in 17 Remington.

Like I said, they all work, picking a coyote rifle is just another way of saying I want a new gun.